Since no one else has responded,I will ask you more information. Are you talking about replacing a damaged (like water-soaked) ECU? About tuning an ECU for more performance in conjunction with intake/exhaust changes? About what happens if you disconnect the battery for an extended period? Provide some context for your questions.
It might need to be programmed, but there is a procedure that you should perform. It is called a proxy alignment, which basically gets all the ECUs in a car synchronized with each other. The dealership can do it, or any independent with a Ferrari specific diagnostic computer (like a Leonardo) should be able to perform the Proxy alignment. Brian Brown San Francisco Motorsports